IARS2 Antibody

Datasheet

Code	CSB-PA229275
Size	US$297
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Image	Western blot analysis of extracts from RAW264.7 cells and COS-7 cells, using IARS2 antibody. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using IARS2 antibody. Immunofluorescence analysis of HepG2 cells, using IARS2 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) IARS2 Polyclonal antibody

Uniprot No.

Q9NSE4

Target Names

IARS2

Alternative Names

2010002H18Rik antibody; C79125 antibody; EC 6.1.1.5 antibody; FLJ10326 antibody; Iars2 antibody; IleRS antibody; isoleucine tRNA ligase 2, mitochondrial antibody; isoleucine tRNA ligase, mitochondrial antibody; isoleucine tRNA synthetase 2, mitochondrial antibody; Isoleucine--tRNA ligase antibody; isoleucine-tRNA synthetase 2 antibody; isoleucyl tRNA synthetase 2, mitochondrial antibody; Isoleucyl-tRNA synthetase antibody; MGC63429 antibody; mitochondrial antibody; mitochondrial isoleucine tRNA synthetase antibody; rCG_20084 antibody; RGD1311857 antibody; SYIM_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from internal of Human IARS2.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB,IHC,IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000
IHC	1:50-1:100
IF	1:100-1:500

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Gene References into Functions

IARS2 silencing induced NSCLC cells growth inhibition, cell cycle arrest and promoted cell apoptosis PMID: 26639235
Patients with this very rare mutation present with a myriad of ocular findings, including infantile cataract, neurotrophic keratitis, corneal opacification, and orbital myopathy. PMID: 27078007
The expression of IARS2 gene is different in human colon cancer and surrounding tissues. IARS2 gene is probably a cancer-promoting gene PMID: 26722399
This study is the first report of clinical findings associated with IARS2 mutations. PMID: 25130867

Involvement in disease

Cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia (CAGSSS)

Subcellular Location

Mitochondrion matrix.

Protein Families

Class-I aminoacyl-tRNA synthetase family

Database Links

HGNC: 29685

OMIM: 612801

KEGG: hsa:55699

STRING: 9606.ENSP00000303279

UniGene: Hs.262823

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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