IFT140 Antibody, Biotin conjugated

Datasheet
Code CSB-PA842756LD01HU
Size US$299
Uniprot No. Q96RY7
Protocols ELISA Protocol
Immunogen Recombinant Human Intraflagellar transport protein 140 homolog protein (1291-1462AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance (PubMed:22503633). May play a role in ciliary assembly. Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells (By similarity).
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2), IFT140, KIAA0590 WDTC2
Immunogen Species Homo sapiens (Human)
Research Area Others
Target Names IFT140
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance
Involvement in disease Short-rib thoracic dysplasia 9 with or without polydactyly (SRTD9)
Subcellular Location Cytoplasm, cytoskeleton, cilium basal body, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cell projection, cilium
Database Links

HGNC: 29077

OMIM: 266920

KEGG: hsa:9742

STRING: 9606.ENSP00000406012

UniGene: Hs.389438

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