IFT74 Antibody

Datasheet

Code	CSB-PA108409
Size	US$166
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Image	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: HepG2 cells, 293T cells, Primary antibody: CSB-PA108409(IFT74 Antibody) at dilution 1/1400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15seconds
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Product Details
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Target Background

Product Details

Uniprot No.

Q96LB3

Target Names

IFT74

Alternative Names

intraflagellar transport 74, Chlamydomonas, homolog of antibody; Capillary morphogenesis gene 1 protein antibody; Capillary morphogenesis protein 1 antibody; Ccdc2 antibody; CMG 1 antibody; CMG-1 antibody; Coiled-coil domain containing 2 antibody; Coiled-coil domain-containing protein 2 antibody; IFT74 antibody; IFT74_HUMAN antibody; intraflagellar transport 74 homolog (Chlamydomonas) antibody; intraflagellar transport 74 homolog antibody; Intraflagellar transport protein 74 homolog antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human IFT74

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis.

Gene References into Functions

this study found that the two core intraflagellar transport proteins IFT74 and IFT81 form a tubulin-binding module and mapped the interaction to a calponin homology domain of IFT81 and a highly basic domain in IFT74. PMID: 23990561
The results revealed that the common variations in IFT74 and GRN neither constitute strong ALS risk factors nor modify the age-at-onset. PMID: 17383054

Involvement in disease

Bardet-Biedl syndrome 20 (BBS20)

Subcellular Location

Cell projection, cilium. Cytoplasmic vesicle. Note=Localizes along primary cilia at interphase and around the basal body/centriole at interphase and mitosis.

Protein Families

IFT74 family

Tissue Specificity

Highly expressed in adult and fetal kidney and expressed at lower level in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. Little to no expression was detected in adult brain and skeletal muscle or in fetal brain, thym

Database Links

HGNC: 21424

OMIM: 608040

KEGG: hsa:80173

STRING: 9606.ENSP00000369402

UniGene: Hs.145402

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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