ILKAP Antibody

Code CSB-PA003037
Size US$100
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  • Western Blot analysis of HeLa cells using ILKAP Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
Alternative Names
DKFZp434J2031 antibody; FLJ10181 antibody; ILKAP antibody; ILKAP_HUMAN antibody; ILKAP2 antibody; ILKAP3 antibody; Integrin linked kinase associated phosphatase antibody; Integrin linked kinase associated serine/threonine phosphatase 2C antibody; Integrin linked kinase associated serine/threonine phosphatase antibody; Integrin-linked kinase-associated serine/threonine phosphatase 2C antibody; MGC4846 antibody; PP2C DELTA antibody; Protein phosphatase 2c delta isozyme antibody
Raised in
Species Reactivity
Synthesized peptide derived from the Internal region of Human ILKAP.
Immunogen Species
Homo sapiens (Human)
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
It differs from different batches. Please contact us to confirm it.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Tested Applications
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.
Gene References into Functions
  1. ILKAP physically interacted with HIF-1A and induced its dephosphorylation. Both the HIF-1A-p53 interaction and apoptosis relied on ILKAP. PMID: 29742494
  2. our data suggest an essential role of PINCH1, ILK and ILKAP for the radioresistance of p53-wildtype glioblastoma multiforme cells PMID: 26460618
  3. The expression of ILKAP was considerably lower in eutopic and ectopic endometrial samples from women with endometriosis than in control endometrium. Expression varied depending on the phase of the menstrual cycle. PMID: 25872452
  4. Data show involvement of ANXA5 and ILKAP in susceptibility to malignant melanoma PMID: 24743186
  5. ILKAP is a nuclear protein that regulates cell survival and apoptosis through the regulation of RSK2 signaling. PMID: 23329845
  6. these results suggested that palladin played a specific role in modulating the subcellular localization of the cytoplasmic ILKAP and promoting the ILKAP-induced apoptosis. PMID: 21782789

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Subcellular Location
Protein Families
PP2C family
Tissue Specificity
Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues.
Database Links

HGNC: 15566

KEGG: hsa:80895

STRING: 9606.ENSP00000254654

UniGene: Hs.92033

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