IMMP2L Antibody

1. While the IMMP2L deletions carried non-recurrent breakpoints, in contrast to previous reports, meta-analysis found no evidence of association (P > 0.05) between IMMP2L deletions and ASD. We also observed common exonic deletions impacting IMMP2L in a separate control (5,971 samples) cohort where subjects were screened for psychiatric conditions. PMID: 29152845
2. data would indicate that deletions involving the IMMP2L gene may contribute to the development of a subgroup of cognitive/behavioral disorders PMID: 29788020
3. Deficiency of IMMP2L in cells cultured under hypoxia and high glucose, exacerbated neuronal death. PMID: 28316022
4. Chromosomal breakpoints involved the IMMP2L gene in 7q31 is associated with Diffuse Large B-Cell Lymphomas. PMID: 27356265
5. IMMP2L transcription requires Topoisomerase I in human primary astrocytes PMID: 27932244
6. genomic rearrangements affecting IMMP2L may be one of the predisposing factors involved in Tourette syndrome and overlapping neurodevelopmental disorders. PMID: 24549057
7. AUTS1/AUTS5 linkage to immp2l-dock4 may be involved in autism susceptibility PMID: 19401682

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HGNC: 14598

OMIM: 137580

KEGG: hsa:83943

STRING: 9606.ENSP00000329553

UniGene: Hs.655722