ITM2A Antibody

Datasheet

Code	CSB-PA011903LA01HU
Size	US$166
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Image	Western blot All lanes: ITM2A antibody at 0.3µg/ml Lane 1: HL60 whole cell lysate Lane 2: SH-SY5Y whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 30, 25 kDa Observed band size: 30 kDa Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA011903LA01HU at dilution of 1:100 Immunofluorescent analysis of A549 cells using CSB-PA011903LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) Immunofluorescent analysis of HepG2 cells using CSB-PA011903LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ITM2A Polyclonal antibody

Uniprot No.

O43736

Target Names

ITM2A

Alternative Names

ITM2A; UNQ603/PRO1189; Integral membrane protein 2A; Protein E25

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Integral membrane protein 2A protein (79-263AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ITM2A Antibody (Product code: CSB-PA011903LA01HU) is Non-conjugated. For ITM2A Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA011903LB01HU	ITM2A Antibody, HRP conjugated	ELISA
FITC	CSB-PA011903LC01HU	ITM2A Antibody, FITC conjugated
Biotin	CSB-PA011903LD01HU	ITM2A Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Gene References into Functions

ITM2A might be a susceptibility gene for Graves disease in the Xq21.1 locus, and environmental factors, such as viral and bacterial infections, probably contribute to GD pathogenesis by interacting with the risk SNP rs3827440 mediating the regulation of ITM2A expression. PMID: 27809695
ITM2A is a new biomarker of poor prognosis in ovarian cancer and a novel tumor suppressor that induces cell cycle arrest, acts as a chemosensitizer, and has therapeutic potential for ovarian cancer. PMID: 26691219
The upregulated gene with the largest effect size in ankylosing spondylitis was ITM2A, which plays a role in activation of T cells. (Meta-analysis) PMID: 26125709
ITM2A expression is positively regulated by PKA-CREB signaling and ITM2A expression interferes with autophagic flux by interacting with vacuolar ATPase. PMID: 25951193
our results show one of the first links between phenotypic variation in a population sample and an XCI-escaping locus and pinpoint ITM2A as a potential contributor to the sexual dimorphism in height PMID: 24516404
Enhanced ITM2A expression inhibits chondrogenic differentiation of mesenchymal stem cells. PMID: 19541402

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Subcellular Location

Membrane; Single-pass type II membrane protein.

Protein Families

ITM2 family

Database Links

HGNC: 6173

OMIM: 300222

KEGG: hsa:9452

STRING: 9606.ENSP00000362395

UniGene: Hs.17109

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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