IVNS1ABP Antibody

Datasheet
Code CSB-PA011923GA01HU
Product Type Purified Rabbit Anti human PolyClonal Antibody
Size US$685
Uniprot No. Q9Y6Y0
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Human IVNS1ABP
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,WB,IHC
Storage Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method Antigen Affinity purified
Isotype IgG
Alias influenza virus NS1A binding protein;IVNS1ABP;DKFZp686K06216;FLARA3;FLJ10069;FLJ10411;FLJ10962;FLJ35593;FLJ36593;HSPC068;KIAA0850;ND1;NS-1;NS1-BP;NS1BP ;
Immunogen Species Homo sapiens (Human)
Target Names IVNS1ABP
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
HGNC 16951
RGD 1306290
MGI 2152389
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Function Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
Subcellular Location Cytoplasm, Cytoplasm, cytoskeleton, Nucleus, nucleoplasm
Database Links

HGNC: 16951

OMIM: 609209

KEGG: hsa:10625

STRING: 9606.ENSP00000356468

UniGene: Hs.497183

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