KBTBD6 Antibody

Code CSB-PA774812LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Hela whole cell lysate
    All lanes: KBTBD6 antibody at 3.4µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 77 kDa
    Observed band size: 77 kDa

  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA774812LA01HU at dilution of 1:100

  • Immunofluorescent analysis of Hela cells using CSB-PA774812LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) KBTBD6 Polyclonal antibody
Uniprot No.
Target Names
KBTBD6
Alternative Names
KBTB6_HUMAN antibody; KBTBD6 antibody; Kelch repeat and BTB (POZ) domain containing 6 antibody; Kelch repeat and BTB domain-containing protein 6 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Kelch repeat and BTB domain-containing protein 6 protein (1-139AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The KBTBD6 Antibody (Product code: CSB-PA774812LA01HU) is Non-conjugated. For KBTBD6 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA774812LB01HU KBTBD6 Antibody, HRP conjugated ELISA
FITC CSB-PA774812LC01HU KBTBD6 Antibody, FITC conjugated
Biotin CSB-PA774812LD01HU KBTBD6 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
As part of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex functions as a substrate adapter for the RAC1 guanine exchange factor (GEF) TIAM1, mediating its 'Lys-48' ubiquitination and proteasomal degradation. By controlling this ubiquitination, regulates RAC1 signal transduction and downstream biological processes including the organization of the cytoskeleton, cell migration and cell proliferation. Ubiquitination of TIAM1 requires the membrane-associated protein GABARAP which may restrict locally the activity of the complex.
Subcellular Location
Cytoplasm. Nucleus.
Database Links

HGNC: 25340

OMIM: 617738

KEGG: hsa:89890

STRING: 9606.ENSP00000368799

UniGene: Hs.534040

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