KIF13A Antibody, Biotin conjugated

Datasheet

Code	CSB-PA880944LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) KIF13A Polyclonal antibody

Uniprot No.

Q9H1H9

Target Names

KIF13A

Alternative Names

bA500C11.2 antibody; FLJ27232 antibody; Homolog of mouse KIF13A mannose 6 phosphate receptor transporter antibody; KI13A_HUMAN antibody; KIF 13A antibody; Kif13a antibody; Kinesin family member 13A antibody; Kinesin like protein KIF13A antibody; Kinesin like protein RBKIN antibody; Kinesin-like protein KIF13A antibody; Kinesin-like protein RBKIN antibody; RBKIN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Kinesin-like protein KIF13A protein (1383-1537AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.

Gene References into Functions

the crystal structure of a catalytically active kinesin-13 monomer (Kif2A) in complex with two bent alphabeta-tubulin heterodimers in a head-to-tail array, providing a view of these interactions, is reported. PMID: 29980677
that KIF13A plays an important role in the transport of influenza A viral ribonucleoproteins PMID: 29061883
KIF13A interacts and cooperates with RAB11 to generate endosomal tubules. PMID: 24462287
kjh kiiou ouiy 8yt 8iy 7i9y PMID: 24859087
the kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization PMID: 21873978
Functionally characterizes the homologous mouse protein. PMID: 11106728
PtdIns(3)P production is essential for proper cytokinesis. PtdIns(3)P-binding centrosomal protein FYVE-CENT and TTC19 control cytokinesis through their translocation from the centrosome to the midbody mediated by the kinesin protein KIF13A. PMID: 20208530
show that the clathrin adaptor AP-1 and the kinesin motor KIF13A together create peripheral recycling endosomal subdomains in melanocytes required for cargo delivery to maturing melanosomes. PMID: 19841138

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Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Endosome membrane. Golgi apparatus membrane. Note=Recruited to the midbody during cytokinesis.

Protein Families

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family

Tissue Specificity

Widely expressed, with highest levels in heart, brain and skeletal muscle.

Database Links

HGNC: 14566

OMIM: 605433

KEGG: hsa:63971

STRING: 9606.ENSP00000259711

UniGene: Hs.94499

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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