KLF17 Antibody

1. Low Expressions of KLF17 is associated with lung adenocarcinoma. PMID: 28454121
2. Suggest that KLF17 inhibits esophageal carcinoma development and may serve as a potential therapeutic target. PMID: 26617836
3. Enhanced KLF17 expression sensitizes ERalpha-positive breast cancer cells to endocrine therapy.KLF17-ERalpha interaction plays a potential role in inhibition of ERalpha-dependent breast cancer progression. PMID: 27107895
4. KLF17 empowers TGF-beta/Smad signaling by targeting Smad3-dependent pathway to suppress tumor growth and metastasis during cancer progression. PMID: 25766320
5. Tumor-suppressive p53 signaling is critical for KLF17 to inhibit cancer metastasis in Non-small Cell Lung Cancer. PMID: 25911104
6. A small subset of Myoepithelial tumors harbor FUS rearrangements, two thirds of them being associated with KLF17 fusion. PMID: 25706482
7. In this review, we focus on the functions, roles, and regulatory networks of these five KLFs in HCC, summarize key pathways, and propose areas for further investigation PMID: 25652467
8. The reduced expression of KLF17 promoted the motility and proliferation ability of TPC1 cells by altering the expression of tight junction protein 1 and Snai1, and activating the AKT pathway by upregulating inhibitor of DNA binding 1. PMID: 25109837
9. mutant p53 enhances cancer progression by inhibiting KLF17 expression in invasive breast carcinoma cells PMID: 25111898
10. The reduced expression of KLF17 protein in gastric cancer was correlated with tumor size, pN stage and lymphovascular invasion and was an independent predictor for poor survival in patients undergoing surgery for gastric cancer. PMID: 24947617
11. KLF17 might be one of the downstream signalling molecules of DJ-1. PMID: 24504364
12. KLF17 may have an oncogenic role during EEC progression via initiating EMT through the regulation of TWIST1 PMID: 24220291
13. Overall, these findings suggest a repressing role of KLF17 in tumor invasion PMID: 23325444
14. it is possible that KLF17 inhibits tumor growth in lung adenocarcinoma. PMID: 22240024
15. KLF17 has a role in transcriptional regulation of metastasis by Id1 [review] PMID: 19951400
16. KLF17 is a new member of the Sp/KLF family of transcription factors. PMID: 16460907
17. demonstrate that KLF17 expression is significantly downregulated in primary human breast cancer samples and that the combined expression pattern of KLF17 and Id1 can serve as a potential biomarker for lymph node metastasis in breast cancer PMID: 19801974

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HGNC: 18830

OMIM: 609602

KEGG: hsa:128209

STRING: 9606.ENSP00000361373

UniGene: Hs.567674