KRT71 Antibody, HRP conjugated

Datasheet

Code	CSB-PA660951LB01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) KRT71 Polyclonal antibody

Uniprot No.

Q3SY84

Target Names

KRT71

Alternative Names

CK-71 antibody; Cytokeratin-71 antibody; hK6irs antibody; hK6irs1 antibody; K2C71_HUMAN antibody; K6IRS1 antibody; K71 antibody; KB34 antibody; Keratin 6 irs antibody; Keratin 6, inner root sheath, 1 antibody; Keratin antibody; keratin, type II cytoskeletal 71 antibody; Keratin-71 antibody; KRT6IRS antibody; KRT6IRS1 antibody; KRT71 antibody; MGC119390 antibody; MGC119391 antibody; OTTHUMP00000236990 antibody; type II cytoskeletal 71 antibody; Type II inner root sheath-specific keratin-K6irs1 antibody; Type-II keratin Kb34 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Keratin, type II cytoskeletal 71 protein (201-500AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle.

Gene References into Functions

Demonstration of the heterozygous mutation c.422T>G (p.Phe141Cys) within the helix initiation motif of the inner root sheath-specific keratin K71 (KRT71) gene in affected family members with autosomal dominant woolly hair/hypotrichosis. PMID: 22592156
A novel epithelial keratin, hK6irs1, is expressed differentially in all layers of the inner root sheath, including specialized huxley cells (Flugelzellen) of the human hair follicle.(HK6IRS1) PMID: 11982755

Involvement in disease

Hypotrichosis 13 (HYPT13)

Subcellular Location

Cytoplasm, cytoskeleton.

Protein Families

Intermediate filament family

Tissue Specificity

Highly expressed in hair follicles from scalp. Specifically expressed in the inner root sheath (IRS) of the hair follicle. Present in the all 3 IRS layers: the cuticle, the Henle and the Huxley layers. Also detected in the pseudopods of specialized Huxley

Database Links

HGNC: 28927

OMIM: 608245

KEGG: hsa:112802

STRING: 9606.ENSP00000267119

UniGene: Hs.660007

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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