KRT81 Antibody

Datasheet

Code	CSB-PA012576LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Hela whole cell lysate, Mouse liver tissue All lanes: KRT81 antibody at 5µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 55 kDa Observed band size: 55 kDa Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA012576LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA012576LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) KRT81 Polyclonal antibody

Uniprot No.

Q14533

Target Names

KRT81

Alternative Names

1 antibody; basic antibody; ghHb 1 antibody; ghHb1 antibody; ghHkb 1 antibody; ghHKb1 antibody; hair antibody; Hair keratin K2.9 antibody; Hard keratin type II 1 antibody; HB 1 antibody; HB1 antibody; hHAKB2 1 antibody; K2.9 antibody; K81 antibody; Keratin 81 antibody; Keratin antibody; Keratin hair basic 1 antibody; Keratin type II cuticular Hb1 antibody; Keratin-81 antibody; Keratin81 antibody; KRT 81 antibody; KRT81 antibody; KRT81_HUMAN antibody; KRTHB 1 antibody; KRTHB1 antibody; Metastatic lymph node 137 gene protein antibody; MLN 137 antibody; MLN137 antibody; type II cuticular Hb1 antibody; Type II hair keratin Hb1 antibody; Type-II keratin Kb21 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Keratin, type II cuticular Hb1 protein (3-505AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The KRT81 Antibody (Product code: CSB-PA012576LA01HU) is Non-conjugated. For KRT81 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA012576LB01HU	KRT81 Antibody, HRP conjugated	ELISA
FITC	CSB-PA012576LC01HU	KRT81 Antibody, FITC conjugated
Biotin	CSB-PA012576LD01HU	KRT81 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Gene References into Functions

Results show that full size KRT81 is expressed in normal breast epithelial cells and breast cancer cells, and indicate that KRT81 contributes to the migration and invasion of breast cancer cells. PMID: 28405679
The analysis of the KRT81rs3660G>C polymorphism may be useful to identify non-small cell lung cancer patients at high risk of a poor disease outcome. PMID: 25716425
Novel mutations causing monilethrix are reported in KRT81, KRT83, and KRT86. PMID: 25557232
MiRNA-related single nucleotide polymorphism sites of KRT81 is associated with non-Hodgkin's lymphoma. PMID: 24530479
Overall survival was significantly longer in multiple myeloma patients with KRT81 rs3660 C/C variant PMID: 22539802
KRT81 has emerged as a promising immunohistochemical marker for the identification of squamous cell lung carcinoma PMID: 21799879
EBV-dependent upregulation of hHb1-DeltaN in gastric carcinoma cell lines PMID: 14520698
The KRTHB1 expression uniformly occurred in the midcortex region. PMID: 15797458
Transfected p65 induces transcriptional activation of Hb1. PMID: 18021261

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Involvement in disease

Monilethrix (MNLIX)

Protein Families

Intermediate filament family

Tissue Specificity

Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. Expressed in malignant lymph node tissue in breast carcinoma ti

Database Links

HGNC: 6458

OMIM: 158000

KEGG: hsa:3887

STRING: 9606.ENSP00000369349

UniGene: Hs.658118

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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