KRT81 Antibody

Code CSB-PA012576GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
KRT81
Alternative Names
1 antibody; basic antibody; ghHb 1 antibody; ghHb1 antibody; ghHkb 1 antibody; ghHKb1 antibody; hair antibody; Hair keratin K2.9 antibody; Hard keratin type II 1 antibody; HB 1 antibody; HB1 antibody; hHAKB2 1 antibody; K2.9 antibody; K81 antibody; Keratin 81 antibody; Keratin antibody; Keratin hair basic 1 antibody; Keratin type II cuticular Hb1 antibody; Keratin-81 antibody; Keratin81 antibody; KRT 81 antibody; KRT81 antibody; KRT81_HUMAN antibody; KRTHB 1 antibody; KRTHB1 antibody; Metastatic lymph node 137 gene protein antibody; MLN 137 antibody; MLN137 antibody; type II cuticular Hb1 antibody; Type II hair keratin Hb1 antibody; Type-II keratin Kb21 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human KRT81
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Results show that full size KRT81 is expressed in normal breast epithelial cells and breast cancer cells, and indicate that KRT81 contributes to the migration and invasion of breast cancer cells. PMID: 28405679
  2. The analysis of the KRT81rs3660G>C polymorphism may be useful to identify non-small cell lung cancer patients at high risk of a poor disease outcome. PMID: 25716425
  3. Novel mutations causing monilethrix are reported in KRT81, KRT83, and KRT86. PMID: 25557232
  4. MiRNA-related single nucleotide polymorphism sites of KRT81 is associated with non-Hodgkin's lymphoma. PMID: 24530479
  5. Overall survival was significantly longer in multiple myeloma patients with KRT81 rs3660 C/C variant PMID: 22539802
  6. KRT81 has emerged as a promising immunohistochemical marker for the identification of squamous cell lung carcinoma PMID: 21799879
  7. EBV-dependent upregulation of hHb1-DeltaN in gastric carcinoma cell lines PMID: 14520698
  8. The KRTHB1 expression uniformly occurred in the midcortex region. PMID: 15797458
  9. Transfected p65 induces transcriptional activation of Hb1. PMID: 18021261

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Involvement in disease
Monilethrix (MNLIX)
Protein Families
Intermediate filament family
Tissue Specificity
Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. Expressed in malignant lymph node tissue in breast carcinoma ti
Database Links

HGNC: 6458

OMIM: 158000

KEGG: hsa:3887

STRING: 9606.ENSP00000369349

UniGene: Hs.658118

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