LANCL1 Antibody

Datasheet

Code	CSB-PA012742GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O43813

Target Names

LANCL1

Alternative Names

40 kDa erythrocyte membrane protein antibody; G protein-coupled receptor 69A antibody; GPR69A antibody; LanC (bacterial lantibiotic synthetase component C) like 1 antibody; LanC lantibiotic synthetase component C like 1 (bacterial) antibody; LanC-like protein 1 antibody; LANC1_HUMAN antibody; LANCL1 antibody; p40 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human LANCL1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione.

Gene References into Functions

Lanthionine synthetase C-like protein 1 interacts with and inhibits cystathionine beta-synthase: a target for neuronal antioxidant defense. PMID: 22891245
the crystal structures of human LanCL1, both free of and complexed with glutathione, revealing glutathione binding to a zinc ion at the putative active site formed by conserved GxxG motifs PMID: 19528316

Subcellular Location

Cytoplasm. Cell membrane; Peripheral membrane protein.

Protein Families

LanC-like protein family

Tissue Specificity

Detected in erythrocytes, brain, kidney, testis, ovary, heart, lung, placenta and spleen (at protein level). Ubiquitous. Strongly expressed in brain, spinal cord, pituitary gland, kidney, heart, skeletal muscle, pancreas, ovary and testis.

Database Links

HGNC: 6508

OMIM: 604155

KEGG: hsa:10314

STRING: 9606.ENSP00000233714

UniGene: Hs.13351

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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