LAYN Antibody

Code CSB-PA012772LA01HU
Size US$166
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  • Immunofluorescence staining of U251 cells with CSB-PA012772LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LAYN Polyclonal antibody
Uniprot No.
Target Names
LAYN
Alternative Names
Layilin antibody; LAYN antibody; LAYN_HUMAN antibody; UNQ208/PRO234 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Layilin protein (262-382AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The LAYN Antibody (Product code: CSB-PA012772LA01HU) is Non-conjugated. For LAYN Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA012772LB01HU LAYN Antibody, HRP conjugated ELISA
FITC CSB-PA012772LC01HU LAYN Antibody, FITC conjugated
Biotin CSB-PA012772LD01HU LAYN Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Receptor for hyaluronate.
Gene References into Functions
  1. Renal biopsy samples from patients with glomerulonephritis showed high expression of LAYN in tubular epithelial cells. PMID: 26410531
  2. results indicate that LAYN would be involved in the enhancement of inflammation and degradation of cartilage in joint diseases such as RA and OA PMID: 25150153
  3. Hyaluronan and layilin mediate loss of airway epithelial barrier function induced by cigarette smoke by decreasing E-cadherin. PMID: 23048036
Subcellular Location
Membrane; Single-pass type I membrane protein.
Database Links

HGNC: 29471

KEGG: hsa:143903

STRING: 9606.ENSP00000364764

UniGene: Hs.503831

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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