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| Code | CSB-PA013048OD01HU |
| Size | US$299 |
| Uniprot No. | Q9HBW0 |
| Protocols | ELISA Protocol |
| Immunogen | Peptide sequence from Human Lysophosphatidic acid receptor 2 protein (8-27AA) |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA |
| Relevance | Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. |
| Form | Liquid |
| Conjugate | Biotin |
| Storage Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method | >95%, Protein G purified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Alias | Lysophosphatidic acid receptor 2 (LPA receptor 2) (LPA-2) (Lysophosphatidic acid receptor Edg-4), LPAR2, EDG4 LPA2 |
| Immunogen Species | Homo sapiens (Human) |
| Research Area | Signal Transduction |
| Target Names | LPAR2 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
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| Function | Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. |
| Subcellular Location | Cell surface, Cell membrane, Multi-pass membrane protein |
| Protein Families | G-protein coupled receptor 1 family |
| Tissue Specificity | Expressed most abundantly in testes and peripheral blood leukocytes with less expression in pancreas, spleen, thymus and prostate. Little or no expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney, ovary, small intestine, or colon. |
| Database Links |
HGNC: 3168 OMIM: 605110 KEGG: hsa:9170 STRING: 9606.ENSP00000384665 UniGene: Hs.122575 |
| Pathway |
PI3K-Akt signaling pathway
Oxidative Phosphorylation Phospholipase D signaling pathway Rap1 signaling pathway |
LPAR2 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA013048OC01HU | LPAR2 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA013048OB01HU | LPAR2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA013048OA01HU | LPAR2 Antibody | Human | ELISA, WB, IHC |
| CSB-PA070246 | LPAR2 Antibody | Human,Mouse,Monkey | WB,IF,ELISA |
| CSB-PA070247 | LPAR2 Antibody | Human | WB,IF,ELISA |
| CSB-PA250941 | LPAR2 Antibody | Human,Mouse | ELISA,IHC |
LPAR2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF013048HU | Recombinant Human Lysophosphatidic acid receptor 2(LPAR2) | in vitro E.coli expression system |
| CSB-YP013048HU1 CSB-EP013048HU1 CSB-BP013048HU1 CSB-MP013048HU1 |
Recombinant Human Lysophosphatidic acid receptor 2(LPAR2),partial | Yeast E.coli Baculovirus Mammalian cell |
2-hydroxyisobutyryl-HIST1H1C (K116) Antibody
Applications: ELISA, ICC, IF, ChIP
Species Reactivity: Human
2-hydroxyisobutyryl-HIST1H4A (K5) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
