LRAT Antibody

Datasheet
Code CSB-PA013069LA01HU
See More Details Free Antibody trial simple
Size US$299
Image
  • Western Blot
    Positive WB detected in: COLO205 whole cell lysate, MCF-7 whole cell lysate
    All lanes: LRAT antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 26 kDa
    Observed band size: 50 kDa

Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) LRAT Polyclonal antibody
Uniprot No. O95237
Target Names LRAT
Alternative Names Lecithin retinol acyltransferase (EC 2.3.1.135) (Phosphatidylcholine--retinol O-acyltransferase), LRAT
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Lecithin retinol acyltransferase protein (24-182AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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Target Data

Function Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments.
Involvement in disease Leber congenital amaurosis 14 (LCA14)
Subcellular Location Endoplasmic reticulum membrane, Single-pass membrane protein, Rough endoplasmic reticulum, Endosome, multivesicular body, Cytoplasm, perinuclear region
Protein Families H-rev107 family
Tissue Specificity Hepatic stellate cells and endothelial cells (at protein level). Found at high levels in testis and liver, followed by retinal pigment epithelium, small intestine, prostate, pancreas and colon. Low expression observed in brain. In fetal tissues, expressed
Database Links

HGNC: 6685

OMIM: 604863

KEGG: hsa:9227

STRING: 9606.ENSP00000337224

UniGene: Hs.658427

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