LRCH1 Antibody

Datasheet
Code CSB-PA897471LA01HU
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Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q9Y2L9
Image
  • Western blot
    All lanes: LRCH1 antibody at 15µg/ml + Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 81, 78, 85 kDa
    Observed band size: 81 kDa

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA897471LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA897471LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunogen Recombinant Human Leucine-rich repeat and calponin homology domain-containing protein 1 protein (1-105AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81), LRCH1, CHDC1 KIAA1016
Immunogen Species Human
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Research Area Cell Biology
Target Names LRCH1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration.
Subcellular Location Cytoplasm
Database Links

HGNC: 20309

OMIM: 610368

KEGG: hsa:23143

STRING: 9606.ENSP00000374447

UniGene: Hs.507971

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