LRCH1 Antibody

Code CSB-PA897471LA01HU
Size US$166
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Image
  • Western blot
    All lanes: LRCH1 antibody at 15µg/ml + Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 81, 78, 85 kDa
    Observed band size: 81 kDa

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA897471LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA897471LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LRCH1 Polyclonal antibody
Uniprot No.
Target Names
LRCH1
Alternative Names
LRCH1 antibody; CHDC1 antibody; KIAA1016 antibody; Leucine-rich repeat and calponin homology domain-containing protein 1 antibody; Calponin homology domain-containing protein 1 antibody; Neuronal protein 81 antibody; NP81 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Leucine-rich repeat and calponin homology domain-containing protein 1 protein (1-105AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The LRCH1 Antibody (Product code: CSB-PA897471LA01HU) is Non-conjugated. For LRCH1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA897471LB01HU LRCH1 Antibody, HRP conjugated ELISA
FITC CSB-PA897471LC01HU LRCH1 Antibody, FITC conjugated
Biotin CSB-PA897471LD01HU LRCH1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration.
Gene References into Functions
  1. In the analysis of hip osteoarthritis cases with superior maximum joint space narrowing (JSN) versus cases with non-superior maximum JSN we detected association with a variant in the LRCH1 gene. PMID: 27974301
  2. Letter: Did not observe an association between LRCH-1 SNPs and knee osteoarthritis. PMID: 22325041
  3. A genetic variant in LRCH1 was consistently associated with knee osteoarthritis in 3 samples from 2 populations. PMID: 16447229
  4. results suggest that there is no association between LRCH1 and knee osteoarthritis susceptibility PMID: 18049793
Subcellular Location
Cytoplasm.
Database Links

HGNC: 20309

OMIM: 610368

KEGG: hsa:23143

STRING: 9606.ENSP00000374447

UniGene: Hs.507971

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