LSAMP Antibody, HRP conjugated

Code CSB-PA013197LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LSAMP Polyclonal antibody
Uniprot No.
Target Names
LSAMP
Alternative Names
IgLON family member 3 antibody; IGLON3 antibody; Lam antibody; LAMP antibody; Limbic system associated membrane protein antibody; Limbic system associated membrane protein precursor antibody; Limbic system-associated membrane protein antibody; LSAMP antibody; LSAMP_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Limbic system-associated membrane protein (168-287AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection.
Gene References into Functions
  1. We detected African-specific SNPs at ZNF649 and LSAMP, with associations of genome-wide significance for ulcerative colitis. PMID: 27693347
  2. A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men PMID: 26844274
  3. The results showed significant allelic and haplotypic associations between LSAMP gene and schizophrenia. PMID: 24491686
  4. The tumor suppressor function of LSAMP is most likely exerted by reducing the proliferation rate of the tumor cells, possibly by indirectly upregulating one or more of the genes HES1, CTAG2 or KLF10. PMID: 24885297
  5. This study presents the first evidence of a possible role of LSAMP gene in mood and anxiety disorders in humans. PMID: 22892717
  6. proteomic assessments of membrane microdomains in prefrontal cortex and validation in two brain series, strongly implicates LAMP, STXBP1 and BASP1 in schizophreina and supports the view of a neuritic and synaptic dysfunction in the neuropathology PMID: 18268500
  7. Single nucleotide polymorphisms of LSAMP is associated with the pathogenesis of coronary artery disease. PMID: 18318786
  8. LSAMP might play a role in pathoaetiology of suicidal behaviour but further studies are needed to understand its exact contribution PMID: 18433483
  9. results show that LSAMP is a novel candidate tumor suppressor gene in osteosarcomas PMID: 19441093
  10. Identification of chromosomal aberrations associated with disease progression and a novel 3q13.31 deletion involving LSAMP gene in osteosarcoma. PMID: 19724913

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Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Protein Families
Immunoglobulin superfamily, IgLON family
Tissue Specificity
Expressed on limbic neurons and fiber tracts as well as in single layers of the superior colliculus, spinal chord and cerebellum.
Database Links

HGNC: 6705

OMIM: 603241

KEGG: hsa:4045

UniGene: Hs.26409

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