LSAMP Antibody

Datasheet

Code	CSB-PA013197LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Rat brain tissue, Rat liver tissue, Mouse brain tissue, Mouse liver tissue All lanes: LSAMP antibody at 4.2μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 38 kDa Observed band size: 38 kDa Immunofluorescence staining of A549 cells with CSB-PA013197LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) LSAMP Polyclonal antibody

Uniprot No.

Q13449

Target Names

LSAMP

Alternative Names

IgLON family member 3 antibody; IGLON3 antibody; Lam antibody; LAMP antibody; Limbic system associated membrane protein antibody; Limbic system associated membrane protein precursor antibody; Limbic system-associated membrane protein antibody; LSAMP antibody; LSAMP_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human Limbic system-associated membrane protein (168-287AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The LSAMP Antibody (Product code: CSB-PA013197LA01HU) is Non-conjugated. For LSAMP Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA013197LB01HU	LSAMP Antibody, HRP conjugated	ELISA
FITC	CSB-PA013197LC01HU	LSAMP Antibody, FITC conjugated
Biotin	CSB-PA013197LD01HU	LSAMP Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection.

Gene References into Functions

We detected African-specific SNPs at ZNF649 and LSAMP, with associations of genome-wide significance for ulcerative colitis. PMID: 27693347
A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men PMID: 26844274
The results showed significant allelic and haplotypic associations between LSAMP gene and schizophrenia. PMID: 24491686
The tumor suppressor function of LSAMP is most likely exerted by reducing the proliferation rate of the tumor cells, possibly by indirectly upregulating one or more of the genes HES1, CTAG2 or KLF10. PMID: 24885297
This study presents the first evidence of a possible role of LSAMP gene in mood and anxiety disorders in humans. PMID: 22892717
proteomic assessments of membrane microdomains in prefrontal cortex and validation in two brain series, strongly implicates LAMP, STXBP1 and BASP1 in schizophreina and supports the view of a neuritic and synaptic dysfunction in the neuropathology PMID: 18268500
Single nucleotide polymorphisms of LSAMP is associated with the pathogenesis of coronary artery disease. PMID: 18318786
LSAMP might play a role in pathoaetiology of suicidal behaviour but further studies are needed to understand its exact contribution PMID: 18433483
results show that LSAMP is a novel candidate tumor suppressor gene in osteosarcomas PMID: 19441093
Identification of chromosomal aberrations associated with disease progression and a novel 3q13.31 deletion involving LSAMP gene in osteosarcoma. PMID: 19724913

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Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Families

Immunoglobulin superfamily, IgLON family

Tissue Specificity

Expressed on limbic neurons and fiber tracts as well as in single layers of the superior colliculus, spinal chord and cerebellum.

Database Links

HGNC: 6705

OMIM: 603241

KEGG: hsa:4045

UniGene: Hs.26409

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Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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