LSM8 Antibody

Code CSB-PA013212LA01HU
Size US$166
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Image
  • IHC image of CSB-PA013212LA01HU diluted at 1:600 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • IHC image of CSB-PA013212LA01HU diluted at 1:600 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LSM8 Polyclonal antibody
Uniprot No.
Target Names
LSM8
Alternative Names
LSM8U6 snRNA-associated Sm-like protein LSm8 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human U6 snRNA-associated Sm-like protein LSm8 protein (2-96AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The LSM8 Antibody (Product code: CSB-PA013212LA01HU) is Non-conjugated. For LSM8 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA013212LB01HU LSM8 Antibody, HRP conjugated ELISA
FITC CSB-PA013212LC01HU LSM8 Antibody, FITC conjugated
Biotin CSB-PA013212LD01HU LSM8 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:500-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
Gene References into Functions
  1. LSm8 controls nuclear accumulation of all LSm2-7 proteins and the number of cytoplasmic processing bodies. PMID: 22875987
Subcellular Location
Nucleus.
Protein Families
SnRNP Sm proteins family
Database Links

HGNC: 20471

OMIM: 607288

KEGG: hsa:51691

STRING: 9606.ENSP00000249299

UniGene: Hs.655046

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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