LY6D Antibody, HRP conjugated

Code CSB-PA613492LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LY6D Polyclonal antibody
Uniprot No.
Target Names
LY6D
Alternative Names
LY6D antibody; E48 antibody; Lymphocyte antigen 6D antibody; Ly-6D antibody; E48 antigen antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Lymphocyte antigen 6D protein (21-98AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May act as a specification marker at earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification.
Gene References into Functions
  1. Study results suggest that OLFM4, LY6D and S100A7 immunoreactivity are associated with an aggressive phenotype of estrogen receptor (ER)-positive breast carcinoma, and these are potent markers for distant metastasis of ER-positive breast cancer patients. PMID: 30137688
  2. LY6D is the most highly up-regulated in HTR-8/SVneo-SP cells and it has potential to maintain cell proliferation of the cells. it is important for the maintenance of the cells. PMID: 26223706
  3. E48 expression was strong and diffuse in non-neoplastic squamous epithelium, and decreased with progression to laryngeal squamous cell carcinoma. Poorly differentiated tumors had fewer E48-positive cells than well- to moderately- differentiated cases. PMID: 23672314
  4. induction of LY6D expression is triggered through a pathway regulated by ATM, CHK2 and p53 PMID: 23075424
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity
Expressed exclusively at the outer cell surface of transitional epithelia and the keratinocyte of stratified squamous epithelia.
Database Links

HGNC: 13348

OMIM: 606204

KEGG: hsa:8581

STRING: 9606.ENSP00000301263

UniGene: Hs.415762

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