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| Code | CSB-PA145666 |
| Former Code(s) | CSB-PA901977 |
| Size | US$299 |
| Uniprot No. | Q9Y5V3 |
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| Immunogen | Fusion protein of Human MAGED1 |
| Raised in | Rabbit |
| Species Reactivity | Human,Mouse,Rat |
| Tested Applications | ELISA,WB,IHC;ELISA:1:2000-1:5000,WB:1:500-1:2000,IHC:1:25-1:100 |
| Relevance | This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method | Antigen affinity purification |
| Isotype | IgG |
| Alias | melanoma antigen family D, 1 |
| Immunogen Species | Homo sapiens (Human) |
| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol |
| Target Names | MAGED1 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3 |
| Subcellular Location | Cytoplasm, Cell membrane, Peripheral membrane protein, Nucleus |
| Tissue Specificity | Expressed in bone marrow stromal cells from both multiple myeloma patients and healthy donors. Seems to be ubiquitously expressed. |
| Database Links |
HGNC: 6813 OMIM: 300224 KEGG: hsa:9500 STRING: 9606.ENSP00000364847 UniGene: Hs.5258 |
| Pathway | Neurotrophin signaling pathway |
MAGED1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA013351GA01HU | MAGED1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA695195 | MAGED1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
MAGED1 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA896916DSR1HU | MAGED1 Antibody | Human | ELISA, WB, IHC |
| CSB-PA896916DSR2HU | MAGED1 Antibody | Human | ELISA, IHC |
MAGED1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP896916HU CSB-EP896916HU CSB-BP896916HU CSB-MP896916HU |
Recombinant Human Melanoma-associated antigen D1(MAGED1) | Yeast E.coli Baculovirus Mammalian cell |
MAGED1 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL013351HU | Human Melanoma-associated antigen D1(MAGED1) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 7.81 pg/mL |
2-hydroxyisobutyryl-HIST1H2BC (K108) Antibody
Applications: ELISA, WB, IF
Species Reactivity: Human, Rat
2-hydroxyisobutyryl-HIST1H2BC (K120) Antibody
Applications: ELISA, WB
Species Reactivity: Human, Rat
2-hydroxyisobutyryl-HIST1H2BC (K20) Antibody
Applications: ELISA, WB, IF
Species Reactivity: Human, Rat
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