MAP4K5 Antibody

Code CSB-PA013440GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
Alternative Names
MAP4K5 antibody; Mitogen-activated protein kinase kinase kinase kinase 5 antibody; EC antibody; Kinase homologous to SPS1/STE20 antibody; KHS antibody; MAPK/ERK kinase kinase kinase 5 antibody; MEK kinase kinase 5 antibody; MEKKK 5 antibody
Raised in
Species Reactivity
Human MAP4K5
Immunogen Species
Homo sapiens (Human)
Purification Method
Antigen Affinity Purified
It differs from different batches. Please contact us to confirm it.
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Gene References into Functions
  1. MAP4K5 expression is decreased or lost in majority of pancreatic ductal adenocarcinoma. PMID: 27023625
  2. TNF signaling leads to oligomerization, ubiquitination, and activation of GCKR and activation of the SAPK pathway in a manner that depends upon TRAF2 polyubiquitination and oligomerization and Ubc13 function PMID: 12591926
  3. The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Han Chinese from Shanghai. PMID: 16699725
Subcellular Location
Protein Families
Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
Tissue Specificity
Ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate.
Database Links

HGNC: 6867

OMIM: 604923

KEGG: hsa:11183

STRING: 9606.ENSP00000013125

UniGene: Hs.130491

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