MAP4K5 Antibody

Datasheet

Code	CSB-PA013440DSR2HU
Size	US$166
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Image	Western blot All lanes: MAP4K5 antibody at 4.2μg/ml + Mouse brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 95 kDa Observed band size: 95 kDa Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA013440DSR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MAP4K5 Polyclonal antibody

Uniprot No.

Q9Y4K4

Target Names

MAP4K5

Alternative Names

MAP4K5 antibody; Mitogen-activated protein kinase kinase kinase kinase 5 antibody; EC 2.7.11.1 antibody; Kinase homologous to SPS1/STE20 antibody; KHS antibody; MAPK/ERK kinase kinase kinase 5 antibody; MEK kinase kinase 5 antibody; MEKKK 5 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Mitogen-activated protein kinase kinase kinase kinase 5 protein (300-480AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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■ Q&A

Just a quick question in regard to 2 antibodies: What is the major difference between PA013440DSR2 and PA013440DSR1HU?

CSB-PA013440DSR2 and CSB-PA013440DSR1HU are basically the same antibodies, but they were raised in two different rabbits.

Target Background

Function

May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

Gene References into Functions

MAP4K5 expression is decreased or lost in majority of pancreatic ductal adenocarcinoma. PMID: 27023625
TNF signaling leads to oligomerization, ubiquitination, and activation of GCKR and activation of the SAPK pathway in a manner that depends upon TRAF2 polyubiquitination and oligomerization and Ubc13 function PMID: 12591926
The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Han Chinese from Shanghai. PMID: 16699725

Subcellular Location

Cytoplasm.

Protein Families

Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily

Tissue Specificity

Ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate.

Database Links

HGNC: 6867

OMIM: 604923

KEGG: hsa:11183

STRING: 9606.ENSP00000013125

UniGene: Hs.130491

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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