MED18 Antibody

Code CSB-PA275975
Size US$297
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  • Western blot analysis of extracts from Jurkat cells and COLO cells, using MED18 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MED18 Polyclonal antibody
Uniprot No.
Target Names
MED18
Alternative Names
FLJ20045 antibody; hMED 18 antibody; hMED18 antibody; Human Mediator of RNA Polymerase II Transcription antibody; MED 18 antibody; med18 antibody; MED18_HUMAN antibody; Mediator complex subunit 18 antibody; Mediator of RNA polymerase II transcription subunit 18 antibody; Mediator of RNA polymerase II transcription subunit 18 homolog antibody; OTTHUMP00000003645 antibody; p28b antibody; TRAP/mediator complex subunit p28b antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from internal of Human MED18.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Gene References into Functions
  1. A novel transcriptional repression mechanism of hMED18 mediated by hCDK8 and further a novel positive role of free CDK/cyclin module in transcriptional activation is described. PMID: 24840924
Subcellular Location
Nucleus.
Protein Families
Mediator complex subunit 18 family
Database Links

HGNC: 25944

OMIM: 612384

KEGG: hsa:54797

STRING: 9606.ENSP00000362948

UniGene: Hs.479911

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