MED18 Antibody

Code CSB-PA871577LA01HU
Size US$166
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Image
  • Western blot
    All lanes: MED18 antibody at 0.8µg/ml + 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 24 kDa
    Observed band size: 24 kDa

  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA871577LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA871577LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MED18 Polyclonal antibody
Uniprot No.
Target Names
MED18
Alternative Names
FLJ20045 antibody; hMED 18 antibody; hMED18 antibody; Human Mediator of RNA Polymerase II Transcription antibody; MED 18 antibody; med18 antibody; MED18_HUMAN antibody; Mediator complex subunit 18 antibody; Mediator of RNA polymerase II transcription subunit 18 antibody; Mediator of RNA polymerase II transcription subunit 18 homolog antibody; OTTHUMP00000003645 antibody; p28b antibody; TRAP/mediator complex subunit p28b antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Mediator of RNA polymerase II transcription subunit 18 protein (35-208AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The MED18 Antibody (Product code: CSB-PA871577LA01HU) is Non-conjugated. For MED18 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA871577LB01HU MED18 Antibody, HRP conjugated ELISA
FITC CSB-PA871577LC01HU MED18 Antibody, FITC conjugated
Biotin CSB-PA871577LD01HU MED18 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Gene References into Functions
  1. A novel transcriptional repression mechanism of hMED18 mediated by hCDK8 and further a novel positive role of free CDK/cyclin module in transcriptional activation is described. PMID: 24840924
Subcellular Location
Nucleus.
Protein Families
Mediator complex subunit 18 family
Database Links

HGNC: 25944

OMIM: 612384

KEGG: hsa:54797

STRING: 9606.ENSP00000362948

UniGene: Hs.479911

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