MED18 Antibody

Datasheet

Code	CSB-PA871577LA01HU
Size	US$166
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Image	Western blot All lanes: MED18 antibody at 0.8µg/ml + 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 24 kDa Observed band size: 24 kDa Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA871577LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA871577LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MED18 Polyclonal antibody

Uniprot No.

Q9BUE0

Target Names

MED18

Alternative Names

FLJ20045 antibody; hMED 18 antibody; hMED18 antibody; Human Mediator of RNA Polymerase II Transcription antibody; MED 18 antibody; med18 antibody; MED18_HUMAN antibody; Mediator complex subunit 18 antibody; Mediator of RNA polymerase II transcription subunit 18 antibody; Mediator of RNA polymerase II transcription subunit 18 homolog antibody; OTTHUMP00000003645 antibody; p28b antibody; TRAP/mediator complex subunit p28b antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Mediator of RNA polymerase II transcription subunit 18 protein (35-208AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The MED18 Antibody (Product code: CSB-PA871577LA01HU) is Non-conjugated. For MED18 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA871577LB01HU	MED18 Antibody, HRP conjugated	ELISA
FITC	CSB-PA871577LC01HU	MED18 Antibody, FITC conjugated
Biotin	CSB-PA871577LD01HU	MED18 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Gene References into Functions

A novel transcriptional repression mechanism of hMED18 mediated by hCDK8 and further a novel positive role of free CDK/cyclin module in transcriptional activation is described. PMID: 24840924

Subcellular Location

Nucleus.

Protein Families

Mediator complex subunit 18 family

Database Links

HGNC: 25944

OMIM: 612384

KEGG: hsa:54797

STRING: 9606.ENSP00000362948

UniGene: Hs.479911

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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