MEF2B Antibody

1. Expression of J chain immunoglobulin and MEF2B are useful in differentiating classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma and primary mediastinal large B-cell lymphoma. PMID: 28851661
2. K4E, Y69H and D83V mutations decrease the capacity of MEF2B to activate transcription and decrease its effects on cell migration. PMID: 26245647
3. Epstein-Barr Virus EBNA1 bound to host genes of high significance for B-cell growth and function, including MEF2B, IL6R, and EBF1. PMID: 26468528
4. We conclude that MEF2B is a valuable marker of normal germinal center B cells, potentially useful in differential diagnosis of small B cell lymphomas. PMID: 26089142
5. MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma. PMID: 23974956
6. MEF2B has a role in myogenic transformation of the epithelial to a myofibroblast phenotype PMID: 22302709
7. The phylogenetic tree result shows that MEF2B may be original because of its difference of sequences and evolutional relation. PMID: 21951798
8. 32% of diffuse large B-cell lymphoma and 89% of follicular lymphoma cases had somatic mutations in MLL2, and 11.4% and 13.4% of DLBCL and FL cases, respectively, had mutations in MEF2B PMID: 21796119
9. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
10. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
11. Crystal structure of the MADS-box/MEF2S domain of human MEF2B bound to a motif of the transcriptional co-repressor Cabin1 and DNA at 2.2 A resolution PMID: 12700764
12. myogenin and myocyte enhancer factor-2 expression are triggered by membrane hyperpolarization during human myoblast differentiation PMID: 15084602
13. The crystal structure of a histone deacetylase 9 (HDAC9)/myocyte enhancer factor-2 (MEF2)/DNA complex reveals that HDAC9 binds to a hydrophobic groove of the MEF2 dimer. PMID: 15567413
14. Study demonstrates that human intestinal cell BCMO1 expression is dependent on the functional cooperation between peroxisome proliferator-activated receptor-gamma and myocyte enhancer factor 2 isoforms. PMID: 16504037
15. MEF2 proteins are an important component in Galpha13-mediated angiogenesis. PMID: 19093215

Show More

Hide All

HGNC: 6995

OMIM: 600661

KEGG: hsa:100271849

STRING: 9606.ENSP00000162023

UniGene: Hs.153629