MEGF8 Antibody, Biotin conjugated

Code CSB-PA773606LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MEGF8 Polyclonal antibody
Uniprot No.
Target Names
MEGF8
Alternative Names
MEGF8 antibody; C19orf49 antibody; EGFL4 antibody; KIAA0817 antibody; Multiple epidermal growth factor-like domains protein 8 antibody; Multiple EGF-like domains protein 8 antibody; Epidermal growth factor-like protein 4 antibody; EGF-like protein 4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Multiple epidermal growth factor-like domains protein 8 protein (495-663AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a negative regulator of hedgehog signaling.
Gene References into Functions
  1. mutations in MEGF8 cause a Carpenter syndrome subtype frequently associated with defective left-right patterning, probably through perturbation of signaling by hedgehog and nodal family members. PMID: 23063620
Involvement in disease
Carpenter syndrome 2 (CRPT2)
Subcellular Location
Membrane; Single-pass type I membrane protein.
Database Links

HGNC: 3233

OMIM: 604267

KEGG: hsa:1954

STRING: 9606.ENSP00000334219

UniGene: Hs.132483

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