MEGF8 Antibody

Code CSB-PA002262
Size US$119
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  • Western Blot analysis of COLO205 cells using EGFL4 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
MEGF8
Alternative Names
MEGF8 antibody; C19orf49 antibody; EGFL4 antibody; KIAA0817 antibody; Multiple epidermal growth factor-like domains protein 8 antibody; Multiple EGF-like domains protein 8 antibody; Epidermal growth factor-like protein 4 antibody; EGF-like protein 4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human EGFL4.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as a negative regulator of hedgehog signaling.
Gene References into Functions
  1. mutations in MEGF8 cause a Carpenter syndrome subtype frequently associated with defective left-right patterning, probably through perturbation of signaling by hedgehog and nodal family members. PMID: 23063620
Involvement in disease
Carpenter syndrome 2 (CRPT2)
Subcellular Location
Membrane; Single-pass type I membrane protein.
Database Links

HGNC: 3233

OMIM: 604267

KEGG: hsa:1954

STRING: 9606.ENSP00000334219

UniGene: Hs.132483

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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