MPP1 Antibody

1. Data suggest that targeting the ATP binding cassette subfamily C member 4 (ABCC4)-membrane palmitoylated protein 1 (MPP1) protein complex can lead to new therapies to improve treatment outcome of acute myeloid leukemia (AML). PMID: 29146910
2. A new perspective on the role of MPP1 in erythroid cells suggests that direct MPP1-flotillins interactions could be the major driving-force behind the formation of raft domains in red blood cells. PMID: 28865798
3. conclusion, the data demonstrates that MPP1 interacts with lipid mixtures in two different model membrane systems. PMID: 28653654
4. Studies indicate that palmitoylated erythrocyte membrane protein p55 (MPP1) and its palmitoylation play a crucial role in lateral membrane organization in erythroid cells. PMID: 25408337
5. MPP1 knockdown significantly affects the activation of MAP-kinase signaling. PMID: 23507198
6. MPP1 gene expression is decreased in both classic and follicular variants of papillary thyroid carcinoma. PMID: 21509594
7. Results show the NMR-derived structure of the human erythroid p55 PDZ domain and propose a possible interaction mode with the C-terminus of glycophorin C. PMID: 16741958
8. MPP1 links the Usher protein network and the Crumbs protein complex in the retina PMID: 17584769
9. p55 binds to two distinct sites within the FERM domain, and the alternatively spliced exon 5 is necessary for the membrane targeting of protein 4.1R in epithelial cells. PMID: 18952129
10. p55-NF2 protein interaction may play a functional role in the regulation of apico-basal polarity and tumor suppression pathways in non-erythroid cells. PMID: 19144871

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HGNC: 7219

OMIM: 305360

KEGG: hsa:4354

STRING: 9606.ENSP00000358547

UniGene: Hs.496984