MRPL12 Antibody

Code CSB-PA298637
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA298637(MRPL12 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA298637(MRPL12 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: CSB-PA298637(MRPL12 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
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Product Details

Uniprot No.
Target Names
MRPL12
Alternative Names
39S ribosomal protein L12 antibody; 39S ribosomal protein L12, mitochondrial antibody; 5c5-2 antibody; FLJ60124 antibody; L12mt antibody; MGC8610 antibody; mitochondrial antibody; Mitochondrial ribosomal protein L12 antibody; MRP-L12 antibody; MRP-L31/34 antibody; MRPL12 antibody; MRPL7 antibody; MRPL7/L12 antibody; RM12_HUMAN antibody; RPML12 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human MRPL12
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
As a component of the mitochondrial large ribosomal subunit, it plays a role in mitochondrial translation. Associates with mitochondrial RNA polymerase to activate transcription.
Gene References into Functions
  1. knock-down of MRPL12 by RNA interference results in instability of POLRMT. PMID: 26586915
  2. This mutation resulted in a decreased steady-state level of MRPL12 protein. PMID: 23603806
  3. the MRPL12 interaction with POLRMT is likely part of a novel regulatory mechanism that coordinates mitochondrial transcription with translation PMID: 17337445
Subcellular Location
Mitochondrion.
Protein Families
Bacterial ribosomal protein bL12 family
Database Links

HGNC: 10378

OMIM: 602375

KEGG: hsa:6182

STRING: 9606.ENSP00000333837

UniGene: Hs.109059

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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