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MRPL12 Antibody

Datasheet
Code CSB-PA879050
Size US$297
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Image
  • Western blot analysis of extracts from COLO cells, using MRPL12 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MRPL12 Polyclonal antibody
Uniprot No.
P52815
Target Names
MRPL12
Alternative Names
39S ribosomal protein L12 antibody; 39S ribosomal protein L12, mitochondrial antibody; 5c5-2 antibody; FLJ60124 antibody; L12mt antibody; MGC8610 antibody; mitochondrial antibody; Mitochondrial ribosomal protein L12 antibody; MRP-L12 antibody; MRP-L31/34 antibody; MRPL12 antibody; MRPL7 antibody; MRPL7/L12 antibody; RM12_HUMAN antibody; RPML12 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human MRPL12.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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MRPL12 Antibodies

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Target Background

Function
As a component of the mitochondrial large ribosomal subunit, it plays a role in mitochondrial translation. Associates with mitochondrial RNA polymerase to activate transcription.
Gene References into Functions
  1. knock-down of MRPL12 by RNA interference results in instability of POLRMT. PMID: 26586915
  2. This mutation resulted in a decreased steady-state level of MRPL12 protein. PMID: 23603806
  3. the MRPL12 interaction with POLRMT is likely part of a novel regulatory mechanism that coordinates mitochondrial transcription with translation PMID: 17337445
Subcellular Location
Mitochondrion.
Protein Families
Bacterial ribosomal protein bL12 family
Database Links

HGNC: 10378

OMIM: 602375

KEGG: hsa:6182

STRING: 9606.ENSP00000333837

UniGene: Hs.109059

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