MRPL44 Antibody

Code CSB-PA436833
Size US$297
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  • Western blot analysis of extracts from COS-7 cells, using MRPL44 antibody.
  • Immunohistochemistry analysis of paraffin-embedded human heart tissue using MRPL44 antibody.
  • Immunofluorescence analysis of HuvEc cells, using MRPL44 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MRPL44 Polyclonal antibody
Uniprot No.
Target Names
MRPL44
Alternative Names
MRPL44 antibody; 39S ribosomal protein L44 antibody; mitochondrial antibody; L44mt antibody; MRP-L44 antibody; EC 3.1.26.- antibody; Mitochondrial large ribosomal subunit protein mL44 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from internal of Human MRPL44.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB,IHC,IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
IHC 1:50-1:100
IF 1:100-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome.
Gene References into Functions
  1. MRPL44 expression may be a representative marker of metabolic phenotype according to OxPhos amount and a useful predictor of lymph node metastasis in Papillary thyroid carcinoma. PMID: 25590838
  2. Decreased MRPL44 affected assembly of the large ribosomal subunit and stability of 16S rRNA leading to complex IV deficiency. PMID: 23315540
Involvement in disease
Combined oxidative phosphorylation deficiency 16 (COXPD16)
Subcellular Location
Mitochondrion.
Protein Families
Ribonuclease III family, Mitochondrion-specific ribosomal protein mL44 subfamily
Database Links

HGNC: 16650

OMIM: 611849

KEGG: hsa:65080

STRING: 9606.ENSP00000258383

UniGene: Hs.203559

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