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MVD Antibody

Datasheet
Code CSB-PA595344
Size US$166
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Image
  • Immunohistochemistry(IHC) - MVD Antibody
    The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA595344(MVD Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
P53602
Target Names
MVD
Alternative Names
Diphosphomevalonate decarboxylase antibody; FP17780 antibody; MDDase antibody; Mevalonate (diphospho) decarboxylase antibody; Mevalonate (diphospho)decarboxylase antibody; Mevalonate pyrophosphate decarboxylase antibody; MPD antibody; Mvd antibody; MVD1_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human MVD
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:25-1:100
Protocols
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
Gene References into Functions
  1. functional importance of R161 and N17 in the binding and orientation of mevalonate diphosphate PMID: 18823933
Involvement in disease
Porokeratosis 7, multiple types (POROK7)
Subcellular Location
Cytoplasm.
Protein Families
Diphosphomevalonate decarboxylase family
Tissue Specificity
Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta.
Database Links

HGNC: 7529

OMIM: 603236

KEGG: hsa:4597

STRING: 9606.ENSP00000301012

UniGene: Hs.252457

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