MYOZ2 Antibody

Code CSB-PA873609LA01HU
Size US$166
Order now
Image
  • Western Blot
    Positive WB detected in: MCF-7 whole cell lysate
    All lanes: MYOZ2 antibody at 4.31µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 30 kDa
    Observed band size: 30 kDa

  • IHC image of CSB-PA873609LA01HU diluted at 1:300 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

  • Immunofluorescence staining of Hela cells with CSB-PA873609LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MYOZ2 Polyclonal antibody
Uniprot No.
Target Names
MYOZ2
Alternative Names
C4orf5 antibody; Calcineurin binding protein calsarcin 1 antibody; Calsarcin 1 antibody; Calsarcin-1 antibody; Calsarcin1 antibody; CMH16 antibody; CS 1 antibody; CS1 antibody; FATZ related protein 2 antibody; FATZ-related protein 2 antibody; Muscle specific protein antibody; MYOZ 2 antibody; MYOZ2 antibody; MYOZ2_HUMAN antibody; Myozenin-2 antibody; Myozenin2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Myozenin-2 protein (90-180AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The MYOZ2 Antibody (Product code: CSB-PA873609LA01HU) is Non-conjugated. For MYOZ2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA873609LB01HU MYOZ2 Antibody, HRP conjugated ELISA
FITC CSB-PA873609LC01HU MYOZ2 Antibody, FITC conjugated
Biotin CSB-PA873609LD01HU MYOZ2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:200-1:500
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Gene References into Functions
  1. may play a modifying role in hypertrophic cardiomyopathy by affecting the penetrance or degree of performance of the MYH7 gene PMID: 28296734
  2. The cardiac phenotype in hypertrophic cardiomyopathy caused by MYOZ2 mutations might be independent of calcineurin activity in the heart. PMID: 22987565
  3. Two missense mutations, S48P substitution and I246M affecting highly conserved amino acids were linked to hereditary Hypertrophic cardiomyopathy characterized by early onset of symptoms, pronounced cardiac hypertrophy, and cardiac arrhythmias. PMID: 17347475
  4. Mutations in MYOZ1 and MYOZ2 are at least very rare events as an underlying disease mechanism for idiopathic or familial DCM PMID: 17434779
  5. Observational study of genotype prevalence. (HuGE Navigator) PMID: 17347475

Show More

Hide All

Involvement in disease
Cardiomyopathy, familial hypertrophic 16 (CMH16)
Subcellular Location
Cytoplasm, myofibril, sarcomere, Z line.
Protein Families
Myozenin family
Tissue Specificity
Expressed specifically in heart and skeletal muscle.
Database Links

HGNC: 1330

OMIM: 605602

KEGG: hsa:51778

STRING: 9606.ENSP00000306997

UniGene: Hs.732122

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
webinars: DT3C facilitates antibody internalization X
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*