NAA20 Antibody

Code CSB-PA015472GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
NAA20
Alternative Names
NAA20 antibody; NAT5 antibody; N-alpha-acetyltransferase 20 antibody; EC 2.3.1.254 antibody; Methionine N-acetyltransferase antibody; N-acetyltransferase 5 antibody; N-terminal acetyltransferase B complex catalytic subunit NAA20 antibody; N-terminal acetyltransferase B complex catalytic subunit NAT5 antibody; NatB complex subunit NAT5 antibody; NatB catalytic subunit antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human NAT5
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration.
Gene References into Functions
  1. The human NatB complex composed of Naa20 (NAT3) and Naa25 (MDM20) N-terminally acetylates Met-Glu-, Met-Asp-, Met-Asn- and Met-Gln- N-termini, and is important for the structure and function of actomyosin fibers and for proper cellular migration. PMID: 22814378
  2. Human N-acetyltransferase complexe NatB consists of human N-acetyltransferase 3 and human MDM20. hNAT3 knockdown results in an increase in G(0)/G(1)-phase cells. PMID: 18570629
  3. hNat3 (NAT5) is the catalytic subunit and hMdm20 the auxiliary subunit of the human NatB N-terminal acetyltransferase complex. This ribosome associated complex acetylates nascent Met-Asp/Glu- polypeptides. PMID: 18570629
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Acetyltransferase family, ARD1 subfamily
Database Links

HGNC: 15908

OMIM: 610833

KEGG: hsa:51126

STRING: 9606.ENSP00000335636

UniGene: Hs.368783

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