Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA015530DSR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA015530DSR2HU at dilution of 1:100
Recombinant human Cytoplasmic protein NCK1 protein (58-377AA)
Raised in :
Species Reactivity :
Tested Applications :
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.
Storage Buffer :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification method :
Antigen Affinity purified
Cytoplasmic protein NCK1 (NCK adaptor protein 1) (Nck-1) (SH2/SH3 adaptor protein NCK-alpha), NCK1, NCK