NETO1 Antibody, HRP conjugated

Code CSB-PA840571LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NETO1 Polyclonal antibody
Uniprot No.
Target Names
NETO1
Alternative Names
AI851453 antibody; BCTL1 antibody; Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 antibody; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1 antibody; BTCL1 antibody; C130005O10Rik antibody; FLJ41325 antibody; Neto1 antibody; NETO1_HUMAN antibody; Neuropilin and tolloid like 1 antibody; Neuropilin and tolloid-like protein 1 antibody; RGD1566269 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Neuropilin and tolloid-like protein 1 protein (367-507AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.
Gene References into Functions
  1. Neto1 is concluded to be a component of amyloid precursor protein /NMDA receptor trafficking complexes PMID: 23621516
  2. no evidence for the association of NETO1 with schizophrenia in the Japanese population PMID: 22205981
  3. Mouse neto1 plays a critical role in spatial learning and memory through the regulation of NMDAR subunit abundance at synapses. PMID: 19243221
Subcellular Location
[Isoform 2]: Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 1]: Secreted.
Tissue Specificity
Isoform 1 and isoform 2 are retina-specific. Isoform 3 is found in retina as well as at lower levels in adult and fetal brain.
Database Links

HGNC: 13823

OMIM: 607973

KEGG: hsa:81832

STRING: 9606.ENSP00000313088

UniGene: Hs.465407

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