NME3 Antibody

Code CSB-PA824161
Size US$166
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  • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Mouse kidney tissue, Primary antibody: CSB-PA824161(NME3 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details

Uniprot No.
Target Names
NME3
Alternative Names
c371H6.2 antibody; DR-nm23 antibody; Expressed in non metastatic cells 3 antibody; NDK 3 antibody; NDK3 antibody; NDK3_HUMAN antibody; NDP kinase 3 antibody; NDP kinase C antibody; NDPK C antibody; NDPKC antibody; NM23 H3 antibody; nm23-H3 antibody; NM23H3 antibody; NME 3 antibody; NME/NM23 nucleoside diphosphate kinase 3 antibody; Nme3 antibody; Non metastatic cells 3 protein expressed in antibody; Nucleoside diphosphate kinase 3 antibody; Nucleoside diphosphate kinase C antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human NME3
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
Gene References into Functions
  1. Thus Tip60 interacts with RNR and NME3 to provide site-specific synthesis of dNTP for facilitating DNA repair in serum-deprived cells which contain low levels of dNTPs. PMID: 26945015
  2. Down-regulated DR-nm23 expression is associated with invasion and metastasis in colorectal cancer. PMID: 23765094
  3. Among genes correlated to nodal metastatic progression, we verified in vitro that NM23-H3 reduced cell motility. PMID: 17900511
Protein Families
NDK family
Database Links

HGNC: 7851

OMIM: 601817

KEGG: hsa:4832

STRING: 9606.ENSP00000219302

UniGene: Hs.514065

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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