NS Antibody, HRP conjugated

Datasheet
Code CSB-PA356065LB01IIE
Size US$299
Uniprot No. P03495
Protocols ELISA Protocol
Immunogen Recombinant Influenza A virus Non-structural protein 1 protein (152-237AA)
Raised in Rabbit
Species Reactivity Influenza A virus
Tested Applications ELISA
Relevance Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1. In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm. Cellular protein synthesis is thereby shut off very early after virus infection. Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Non-structural protein 1 (NS1) (NS1A), NS
Immunogen Species Influenza A virus (strain A/Udorn/307/1972 H3N2)
Research Area Others
Target Names NS
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Still Have Questions? Leave a Message or Start an on-line Chat
Function Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs
Subcellular Location Host nucleus, Host cytoplasm
Protein Families Influenza A viruses NS1 family

Related Products

NS Antibodies

NS Antibodies for Influenza A virus (strain A/Udorn/307/1972 H3N2)

NS Proteins

NS Proteins for Influenza A virus (strain A/Udorn/307/1972 H3N2)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.