NS1 Antibody, Biotin conjugated

Code CSB-PA357083LD01HPM
Size US$166
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Product Details

Full Product Name
Rabbit anti-Human parvovirus B19 NS1 Polyclonal antibody
Uniprot No.
Target Names
NS1
Alternative Names
NS1 antibody; Initiator protein NS1 antibody; NS1 antibody; EC 3.1.21.- antibody; EC 3.6.4.12 antibody; NCVP1 antibody; Non-capsid protein NS-1 antibody; Non-structural protein 1 antibody; Non-structural protein NS1 antibody
Raised in
Rabbit
Species Reactivity
Human parvovirus B19
Immunogen
Recombinant Human parvovirus B19 Non-capsid protein NS-1 protein (1-255AA)
Immunogen Species
Human parvovirus B19
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Multifunctional protein essential for viral DNA replication, which cooperatively interacts with the viral DNA origin of replication and transactivates several promoters including the viral p6 promoter. Binds the origin of replication and performs an endonucleolytic nick within a conserved sequence in the viral genome, thereby initiating the rolling circle replication (RCR). Participates in the transcriptional regulation the viral p6 promoter that regulates all viral transcripts and the cellular CDN1A or IL6 promoters. Transactivates several host promoters some of which induce the S cell cycle phase for the production of host replicative proteins. Upregulates the expression of host E2F4 and E2F5 and interacts with both these factors thereby inhibiting the host cell cycle G2/M transition. This arrest promotes apoptosis for viral release.
Subcellular Location
Host nucleus.
Protein Families
Parvoviruses non-capsid protein family
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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