NUBPL Antibody

Code CSB-PA819450LA01HU
Size US$166
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  • Western blot
    All lanes: NUBPL antibody at 1µg/ml + A431 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 35, 19 kDa
    Observed band size: 35 kDa

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA819450LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA819450LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NUBPL Polyclonal antibody
Uniprot No.
Target Names
NUBPL
Alternative Names
C14orf127 antibody; FLJ12660 antibody; huInd1 antibody; IND1 homolog antibody; Iron-sulfur protein NUBPL antibody; Nubpl antibody; NUBPL_HUMAN antibody; nucleotide binding protein like antibody; Nucleotide-binding protein-like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Iron-sulfur protein NUBPL protein (39-319AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The NUBPL Antibody (Product code: CSB-PA819450LA01HU) is Non-conjugated. For NUBPL Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA819450LB01HU NUBPL Antibody, HRP conjugated ELISA
FITC CSB-PA819450LC01HU NUBPL Antibody, FITC conjugated
Biotin CSB-PA819450LD01HU NUBPL Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). May deliver of one or more Fe-S clusters to complex I subunits.
Gene References into Functions
  1. huInd1 binds to the untranslated region of the TEM-1 mRNA at 3' site and thereby reducing the possibility of its endonucleolytic cleavage, resulting in over-expression of TEM-1. PMID: 25240856
  2. Inhibition of ERK suppressed the NUBPL-induced changes in EMT and cell motility. PMID: 28346728
  3. Our data show that NUBPL mutations are associated with a unique, consistent, and recognizable MRI pattern. PMID: 23553477
  4. Mutations in NUBPL is associated with complex I deficiency. PMID: 20818383
  5. These data identify huInd1 as a new assembly factor for human respiratory complex I with a possible role in the delivery of one or more Fe/S clusters to complex I subunits.[Ind1] PMID: 19752196

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Involvement in disease
Mitochondrial complex I deficiency (MT-C1D)
Subcellular Location
Mitochondrion.
Protein Families
Mrp/NBP35 ATP-binding proteins family
Tissue Specificity
Highest expression in liver and kidney. expressed at significant levels in small intestine and brain (at protein level).
Database Links

HGNC: 20278

OMIM: 252010

KEGG: hsa:80224

STRING: 9606.ENSP00000281081

UniGene: Hs.288981

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