NUP133 Antibody

Datasheet

Code	CSB-PA016189GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q8WUM0

Target Names

NUP133

Alternative Names

133 kDa nucleoporin antibody; FLJ10814 antibody; hNUP 133 antibody; hNUP133 antibody; MGC21133 antibody; NU133_HUMAN antibody; Nuclear pore complex protein Nup133 antibody; Nucleoporin 133kDa antibody; Nucleoporin NUP133 antibody; NUP 133 antibody; NUP133 antibody; OTTHUMP00000061095 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human NUP133

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Involved in poly(A)+ RNA transport. Involved in nephrogenesis.

Gene References into Functions

human Nup133 contains two domains: a COOH-terminal domain responsible for its interaction with its subcomplex through Nup107; and an NH2-terminal domain whose crystal structure reveals a seven-bladed beta-propeller. PMID: 15557116
When complexed with NUP107, this complex will give the first insights into the protein-protein interactions within a core module of the nuclear pore complex. PMID: 17768364
The significant topological differences between Nup107 and Nup133 suggest that helical nucleoporin domains of the nuclear pore complex scaffold fall in different classes and fulfill largely nonredundant functions. PMID: 18570875
Data present crystal structures of yNup170(979-1502) and hNup107(658-925) x hNup133(517-1156), and conservation of domain arrangement and of tertiary structure suggests that Nup157/170 and Nup133 derived from a common ancestor. PMID: 19674973

Subcellular Location

Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore.

Protein Families

Nucleoporin Nup133 family

Tissue Specificity

Widely expressed in fetal and adult tissues. Expressed in the brain and kidney.

Database Links

HGNC: 18016

OMIM: 607613

KEGG: hsa:55746

STRING: 9606.ENSP00000261396

UniGene: Hs.12457

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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