NUP88 Antibody

1. Overexpression of the NUP88 is associated with cancer. PMID: 27636375
2. Nup88 may be related to the occurrence of endometrial cancers and premalignant lesions PMID: 26839161
3. These findings demonstrate that the NUP88-NUP98-RAE1-APC/CCDH1 axis contributes to aneuploidy PMID: 26731471
4. Nup62 and Nup88 protein levels were significantly decreased upon knockdown of O-GlcNAc transferase. PMID: 23777819
5. Serum Nup88 might be a candidate for a new biomarker implicated in the development and aggressiveness of colorectal cancer PMID: 21863385
6. Nup88 mRNA was overexpressed in colorectal cancers and the overexpression was associated with cancer development and aggressiveness. PMID: 21896994
7. Data suggest that a pool of Nup88 on the nuclear side of the nuclear pore complex provides a novel, unexpected binding site for nuclear lamin A. PMID: 21289091
8. association found between myometrial invasion and Nup88 expression in endometrial carcinoma PMID: 20973273
9. Gambogic acid exerts its anti-leukemia effects by regulating the expression and distribution of nucleoporin Nup88. PMID: 17828493
10. proper expression of Nup88 is critical for preventing aneuploidy formation and tumorigenesis. PMID: 20497554
11. High Nup88 mRNA expression levels correlated with ductal and tubular histology, nuclear grade 3, absence of hormone receptors, expression of c-erb-B2 oncogene and mutant p53 protein, high proliferation, DNA aneuploidy, and axillary node invasion. PMID: 14999780
12. A monoclonal antibody for Nup88 in an experimental model for studying the role played by Nup88 during cell development and differentiation. PMID: 15300515
13. the Nup214-Nup88 nucleoporin subcomplex is required for CRM1-mediated 60 S preribosomal nuclear export PMID: 16675447
14. Our data strongly indicate a dichotomous role for Nup88 in non-neoplastic and neoplastic conditions of the liver. PMID: 17007055
15. The antitumor activity of deguelin was related to up-regulating the expression of Nup98 and down-regulating Nup88 protein. PMID: 17650673
16. The formation of high molecular mass complexes containing importin-alpha, Nup153 and Nup88 is increased upon oxidant treatment. PMID: 18068677
17. Nup88 is up-regulated in response to hypertonic stress and acts to retain TonEBP in the nucleus, activating transcription of critical osmoprotective genes. PMID: 18606815
18. Nup88 is significantly overexpressed in high-grade CIN lesions and ISCC compared with normal ectocervical squamous epithelia and CIN1. PMID: 19751906

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HGNC: 8067

OMIM: 602552

KEGG: hsa:4927

STRING: 9606.ENSP00000458954

UniGene: Hs.584784