OAZ3 Antibody

Datasheet

Code	CSB-PA016247LA01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) OAZ3 Polyclonal antibody

Uniprot No.

Q9UMX2

Target Names

OAZ3

Alternative Names

Antizyme 3 antibody; AZ3 antibody; OAZ t antibody; OAZ3 antibody; OAZ3_HUMAN antibody; ODC-Az 3 antibody; Ornithine decarboxylase antizyme 3 antibody; RP11-98D18.13-004 antibody; Testicular secretory protein Li 31 antibody; TISP15 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Ornithine decarboxylase antizyme 3 protein (1-190AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The OAZ3 Antibody (Product code: CSB-PA016247LA01HU) is Non-conjugated. For OAZ3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA016247LB01HU	OAZ3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA016247LC01HU	OAZ3 Antibody, FITC conjugated
Biotin	CSB-PA016247LD01HU	OAZ3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity. Stabilizes AZIN2 by interfering with its ubiquitination. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. Probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells.

Gene References into Functions

Mutations in the OAZ3 gene are not a common cause of male infertility. PMID: 16542438
antizyme expression requires programmed, ribosomal frameshifting PMID: 10781085

Subcellular Location

Nucleus. Cytoplasm.

Protein Families

ODC antizyme family

Tissue Specificity

Testis specific.

Database Links

HGNC: 8097

OMIM: 605138

KEGG: hsa:51686

STRING: 9606.ENSP00000415904

UniGene: Hs.713789

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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