OAZ3 Antibody, Biotin conjugated

Code CSB-PA016247LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) OAZ3 Polyclonal antibody
Uniprot No.
Target Names
OAZ3
Alternative Names
Antizyme 3 antibody; AZ3 antibody; OAZ t antibody; OAZ3 antibody; OAZ3_HUMAN antibody; ODC-Az 3 antibody; Ornithine decarboxylase antizyme 3 antibody; RP11-98D18.13-004 antibody; Testicular secretory protein Li 31 antibody; TISP15 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ornithine decarboxylase antizyme 3 protein (1-190AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity. Stabilizes AZIN2 by interfering with its ubiquitination. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. Probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells.
Gene References into Functions
  1. Mutations in the OAZ3 gene are not a common cause of male infertility. PMID: 16542438
  2. antizyme expression requires programmed, ribosomal frameshifting PMID: 10781085
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
ODC antizyme family
Tissue Specificity
Testis specific.
Database Links

HGNC: 8097

OMIM: 605138

KEGG: hsa:51686

STRING: 9606.ENSP00000415904

UniGene: Hs.713789

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