OSGEP Antibody

Datasheet

Code	CSB-PA878842ESR1HU
Size	US$166
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Image	Western blot All lanes: OSGEP antibody at 3.18µg/ml Lane 1: 293T whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: Raji whole cell lysate Lane 4: PC-3 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 36 kDa Observed band size: 36 kDa Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA878842ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) OSGEP Polyclonal antibody

Uniprot No.

Q9NPF4

Target Names

OSGEP

Alternative Names

FLJ20411 antibody; GCPL-1 antibody; GCPL1 antibody; hOSGEP antibody; KAE1 antibody; O sialoglycoprotein endopeptidase antibody; OSGEP antibody; OSGEP_HUMAN antibody; OSGEP1 antibody; Pasteurella haemolytica metalloprotease homolog with glycoprotein substrates/gpc-like protein 1 antibody; Probable O sialoglycoprotein endopeptidase antibody; Probable tRNA threonylcarbamoyladenosine biosynthesis protein osgep antibody; PRSMG1 antibody; Prsmg1/Gcpl1 antibody; t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Probable tRNA N6-adenosine threonylcarbamoyltransferase protein (1-335AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.

Gene References into Functions

Mutation in KAE1 interfering with global protein production was identified in two patients with developmental delay, renal defect and hypomagnesemia. PMID: 28272532

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

KAE1 / TsaD family

Tissue Specificity

Widely expressed at low level. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas.

Database Links

HGNC: 18028

OMIM: 610107

KEGG: hsa:55644

STRING: 9606.ENSP00000206542

UniGene: Hs.525196

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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