OTOG Antibody, Biotin conjugated

Datasheet
Code CSB-PA017273LD01HU
Size US$299
Uniprot No. Q6ZRI0
Immunogen Recombinant Human Otogelin protein (1634-1796AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes (By similarity).
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Otogelin, OTOG, OTGN
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Others
Target Names OTOG
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes (By similarity).
Involvement in disease Deafness, autosomal recessive, 18B (DFNB18B)
Subcellular Location Apical cell membrane, Peripheral membrane protein, Extracellular side, Secreted, extracellular space
Protein Families Otogelin family
Database Links

HGNC: 8516

OMIM: 604487

KEGG: hsa:340990

STRING: 9606.ENSP00000382323

UniGene: Hs.688380

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