OTUB2 Antibody

Datasheet

Code	CSB-PA076030
Size	US$166
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Image	Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human liver cancer tissue, Primary antibody: CSB-PA076030(OTUB2 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

Q96DC9

Target Names

OTUB2

Alternative Names

C14orf137 antibody; Deubiquitinating enzyme OTUB2 antibody; FLJ21916 antibody; MGC3102 antibody; OTB2 antibody; OTU domain containing ubiquitin aldehyde binding protein 2 antibody; OTU domain, ubiquitin aldehyde binding 2 antibody; OTU domain-containing ubiquitin aldehyde-binding protein 2 antibody; OTU2 antibody; Otub2 antibody; OTUB2_HUMAN antibody; Otubain 2 antibody; Otubain-2 antibody; Ubiquitin specific processing protease OTUB2 antibody; Ubiquitin specific protease otubain 2 antibody; Ubiquitin thioesterase OTUB2 antibody; Ubiquitin-specific-processing protease OTUB2 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Fusion protein of Human OTUB2

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains.

Gene References into Functions

OTUB2 fine-tunes the speed of double-strand break-induced ubiquitination so that the appropriate DNA repair pathway is chosen PMID: 24560272
OTUB2 is a novel promoter of viability and insulin secretion in human beta cells. OTUB2 acts through the inhibition of NF-kappaB signalling. PMID: 23515685
Data report the first crystal structure of an OTU superfamily protein, otubain 2, at 2.1 A resolution and propose a model for otubain-ubiquitin binding. PMID: 15258613

Protein Families

Peptidase C65 family

Tissue Specificity

Widely expressed. Expressed at higher level in brain.

Database Links

HGNC: 20351

OMIM: 608338

KEGG: hsa:78990

STRING: 9606.ENSP00000203664

UniGene: Hs.278815

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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